SCHEMBL16812840

SCHEMBL16812840

C=CC(=O)CCc1ccc(Cc2ccc(Cc3ccc(CCC(=O)C=C)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.43
GPR52 Q9Y2T5 1/20 0.42
BCHE P06276 2/20 0.41
ACHE P22303 2/20 0.41
TBXAS1 P24557 2/20 0.41
FFAR1 O14842 1/20 0.41
THRA P10827 5/20 0.41
POLB P06746 1/20 0.39
KMT2A Q03164 2/20 0.39
KEAP1 Q14145 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13310792 0.96 THRB (0.46) THRBGPR52BCHEACHETBXAS1
SCHEMBL13310793 0.89 THRB (0.50) THRBGPR52BCHEACHEFFAR1
SCHEMBL17897411 0.88 FFAR1 (0.52) THRBGPR52BCHEACHEFFAR1
SCHEMBL15272414 0.86 ESR1 (0.50) THRBPOLBKMT2AMEN1
SCHEMBL22522171 0.84 HDAC1 (0.49) FFAR1KMT2AMEN1
SCHEMBL22522189 0.84 FFAR1 (0.50) THRBBCHEACHEFFAR1THRA
Hydrochloric Acid SCHEMBL27699853 0.84 ESR1 (0.48) THRBPOLBKMT2AMEN1
SCHEMBL27538965 0.84 ALDH1A1 (0.42) THRBGPR52BCHEACHEFFAR1
SCHEMBL4424144 0.83 GPR52 (0.59) GPR52FFAR1KMT2AKEAP1
Hydrochloric Acid SCHEMBL27720366 0.82 GPR52 (0.58) GPR52FFAR1KMT2AKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-9410086-B2 Liquid crystal-polymer composite material DIC CORPORATION (JP) 2016-08-09 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed
US-20150166893-A1 LIQUID CRYSTAL-POLYMER COMPOSITE MATERIAL DIC Corporation (Tokyo) (JP) 2015-06-18 US disclosed