SCHEMBL16816475

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17013486	0.89	ALDH1A1 (0.59)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL28415492	0.89	ALDH1A1 (0.61)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL16816712	0.88	PDE5A (0.48)	ALDH1A1HTTPDE5AKMT2AMEN1
	SCHEMBL29972749	0.87	PDE5A (0.59)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL31694381	0.87	PDE5A (0.59)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL1679801	0.87	PDE5A (0.59)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL16816549	0.83	ALDH1A1 (0.57)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL17013474	0.83	ALDH1A1 (0.56)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL16815886	0.82	ALDH1A1 (0.55)	ALDH1A1SYKMAPK1HTTMAPT
	SCHEMBL4712695	0.82	ALDH1A1 (0.65)	ALDH1A1SYKMAPK1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.