Mandelic Acid

Mandelic Acid

SCHEMBL1681663

O=C(O)C(O)c1ccccc1.[AlH3]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.95
MAPK1 P28482 1/20 0.95
CES2 O00748 2/20 0.60
CES1 P23141 2/20 0.60
SRC P12931 2/20 0.56
CYP2D6 P10635 1/20 0.56
HPGD P15428 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN7 P35236 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
ESR2 Q92731 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL1681662 1.00 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL21647917 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL165161 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL29777368 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL255601 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1050 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL5313046 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1374278 0.95 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1680817 0.95 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL9188111 0.95 LMNA (0.95) LMNAMAPK1CES2CES1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2488579-B1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2017-05-03 EP disclosed
US-8779045-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2014-07-15 US disclosed
CN-102798696-A Method for continuously determining contents of Fe, Al and Ti in high-alumina bauxite powder JIANGSU NANCI INSULATORS CO LTD 2012-11-28 CN disclosed
EP-2488579-A1 THERMOPLASTIC POLYMER COMPOSITION Milliken & Company (US) 2012-08-22 EP disclosed
US-20110105664-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY 2011-05-05 US disclosed
WO-2011047108-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY (US) 2011-04-21 WO disclosed
US-5463086-A Dissolving a crude lactide in a weak and strong solvent mixture then recrystallizing DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-10-31 US disclosed