Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031278 | 0.87 | LOX (0.38) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL17997014 | 0.86 | ALDH1A1 (0.64) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL19695399 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL14845475 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9ABCG2 | |
| SCHEMBL16898333 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9ABCG2 | |
| SCHEMBL13497897 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9ABCG2 | |
| SCHEMBL16898565 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9ABCG2 | |
| SCHEMBL16898408 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9ABCG2 | |
| SCHEMBL31395440 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9ABCG2 | |
| SCHEMBL18858985 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9539336-B2 | Sialic acid derivatives | BROSSMER REINHARD (DE) | 2017-01-10 | — | — | US | disclosed |
| US-20150174262-A1 | Sialic Acid Derivatives | BROSSMER REINHARD (DE) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174262-A1 | Sialic Acid Derivatives | NEU1, SIGLEC9, SIGLEC7 | ALDH1A1 414/4885CYP2C19 1647/4885CYP3A4 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.