Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.42 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694401 | 0.84 | NOS1 (0.51) | KMT2AMEN1NOS1ALDH1A1TSHR | |
| SCHEMBL168738 | 0.84 | FOLH1 (0.59) | KMT2AMEN1ALDH1A1TSHRMEP1B | |
| SCHEMBL29630981 | 0.84 | FOLH1 (0.59) | KMT2AMEN1ALDH1A1TSHRMEP1B | |
| Hydrochloric Acid SCHEMBL15067497 | 0.82 | FOLH1 (0.58) | KMT2AMEN1ALDH1A1TSHRMEP1B | |
| SCHEMBL2911625 | 0.82 | MEP1B (0.59) | KMT2AMEN1NOS1MEP1BROCK2 | |
| Hydrochloric Acid SCHEMBL29690742 | 0.82 | FOLH1 (0.58) | KMT2AMEN1ALDH1A1TSHRMEP1B | |
| Hydrochloric Acid SCHEMBL3863131 | 0.81 | MEP1B (0.57) | KMT2AMEN1NOS1MEP1BROCK2 | |
| SCHEMBL27379923 | 0.81 | KMT2A (0.46) | KMT2AMEN1NOS1ALDH1A1TSHR | |
| SCHEMBL12669377 | 0.81 | KMT2A (0.46) | KMT2AMEN1NOS1ALDH1A1TSHR | |
| SCHEMBL40196 | 0.79 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1TSHRMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |