Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822755 | 1.00 | GGT1 (0.62) | GGT1RAB9AALDH1A1KMT2ACYP2D6 | |
| SCHEMBL3451052 | 0.91 | ALDH1A1 (0.54) | GGT1RAB9AALDH1A1KMT2ACYP2D6 | |
| SCHEMBL3451049 | 0.91 | ALDH1A1 (0.54) | GGT1RAB9AALDH1A1KMT2ACYP2D6 | |
| SCHEMBL19419067 | 0.88 | GGT1 (0.65) | GGT1RAB9AALDH1A1KMT2ACYP2D6 | |
| SCHEMBL2248518 | 0.85 | GGT1 (0.67) | GGT1RAB9AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL29257628 | 0.84 | GGT1 (0.65) | GGT1RAB9AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL19418932 | 0.83 | GGT1 (0.59) | GGT1ALDH1A1KMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL18645284 | 0.83 | GGT1 (0.67) | GGT1RAB9AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL4560841 | 0.83 | GGT1 (0.67) | GGT1RAB9AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL27507225 | 0.83 | GGT1 (0.67) | GGT1RAB9AKMT2ACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175578-A1 | COMPOSITIONS AND METHODS FOR TREATMENT | SARCODE BIOSCIENCE INC. (US) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175578-A1 | COMPOSITIONS AND METHODS FOR TREATMENT | ICAM1, VCAM1, ITGAL | GGT1 957/4885RAB9A 2495/4885ALDH1A1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.