Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | L3MBTL3 | Q96JM7 | 12/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.57 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.57 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823941 | 0.87 | MEN1 (0.59) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL16823894 | 0.87 | ADRA1A (0.61) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL16823958 | 0.86 | MEN1 (0.60) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL12412643 | 0.86 | MEN1 (0.62) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10202499 | 0.86 | L3MBTL3 (0.77) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL16823981 | 0.85 | MEN1 (0.60) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL16823771 | 0.84 | MEN1 (0.54) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL6504711 | 0.83 | MEN1 (0.75) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16845192 | 0.82 | MEN1 (0.54) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL16845195 | 0.81 | L3MBTL3 (0.57) | MEN1KMT2AL3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-03 | — | — | US | disclosed |
| EP-3083594-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | Bayer Pharma Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091415-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015091415-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | TNNI3, TNNC1, FABP3 | MEN1 3937/4885KMT2A 4876/4885L3MBTL3 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.