SCHEMBL16826014

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL474171	0.76	NOTUM (0.61)	KDM4EALDH1A1MAPTBLMNOTUM
	SCHEMBL16826106	0.75	NOTUM (0.64)	KDM4EALDH1A1MAPTBLMNOTUM
	SCHEMBL4318582	0.75	NPC1 (0.64)	MAPTNOTUMNPC1RAB9A
	SCHEMBL4322944	0.73	NPC1 (0.67)	ALDH1A1NOTUMCYP2C9CYP2C19CYP11B1
	SCHEMBL4331569	0.72	NPC1 (0.53)	ALDH1A1MAPTNOTUMNPC1RAB9A
	SCHEMBL4315882	0.72	NPC1 (0.42)	CYP2C9CYP2C19CYP11B1CYP11B2NPC1
	SCHEMBL12598638	0.71	CYP2A6 (0.64)	MKNK1MKNK2KDM4EALDH1A1MAPT
	SCHEMBL4316645	0.71	CYP2C9 (0.53)	MAPTCYP2E1CYP2A6CYP2C9CYP2B6
	SCHEMBL4324363	0.71	NPC1 (0.59)	MAPTNPC1RAB9A
	SCHEMBL4324017	0.71	NPC1 (0.41)	MKNK1MKNK2CYP2C9CYP2C19CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.