SCHEMBL168292

SCHEMBL168292

C=C(C)C(=O)NC[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TGFBR1 P36897 1/20 0.33
THRB P10828 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6066883 0.82 ALDH1A1 (0.38) ALDH1A1TGFBR1
SCHEMBL170367 0.82 ALDH1A1 (0.38) ALDH1A1TGFBR1
SCHEMBL6066974 0.82 ALDH1A1 (0.38) ALDH1A1TGFBR1
SCHEMBL6067457 0.80 THRB (0.36) ALDH1A1TGFBR1THRBMGAMGAA
SCHEMBL23455658 0.80 ALDH1A1 (0.32) ALDH1A1TGFBR1
SCHEMBL135382 0.79 ALDH1A1 (0.35) ALDH1A1
SCHEMBL13317345 0.78 KDM4E (0.39) ALDH1A1MGAMGAASIMGAM2
SCHEMBL15641849 0.77 KDM4E (0.38) ALDH1A1
SCHEMBL29440661 0.77 THRB (0.34) ALDH1A1TGFBR1THRB
SCHEMBL27531303 0.77 ALDH1A1 (0.34) ALDH1A1TGFBR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2158283-B1 MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-10-18 EP claimed
US-8063140-B2 Moisture-curable, graft-modified resin composition, process for its manufacture and process for bonding substrates employing the resin composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-11-22 US claimed
EP-2158283-A1 MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION Momentive Performance Materials Inc. (US) 2010-03-03 EP claimed
WO-2009147024-A1 BINDERS BASED ON POLYMERS CONTAINING ALPHA-SILANE GROUPS WACKER CHEMIE AG (DE) 2009-12-10 WO claimed
WO-2008156611-A1 MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-12-24 WO claimed
US-20080311419-A1 Moisture-curable, graft-modified resin composition, process for its manufacture and process for bonding substrates employing the resin composition MOMENTIVE PERFORMANCE MATERIALS INC. 2008-12-18 US claimed
US-20250179251-A1 COMPOSITION COMPRISING METHACRYLAMIDE GROUP-CONTAINING ORGANIC SILICON COMPOUND AND ARTICLE SURFACE-TREATED WITH SAID COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-05 US disclosed
WO-2025093733-A1 RTV-1 SILICONE COMPOSITION WHICH IS CATALYZED IN A TIN-FREE MANNER AND WHICH HAS IMPROVED STORAGE STABILITY SIKA TECHNOLOGY AG (CH) 2025-05-08 WO disclosed
EP-4384485-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS Wacker Chemie AG (DE) 2024-06-19 EP disclosed
WO-2024094292-A1 MULTI-STAGE COPOLYMERS AS BINDER FOR COATING AGENTS WACKER CHEMIE AG (DE) 2024-05-10 WO disclosed
WO-2023016627-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS WACKER CHEMIE AG (DE) 2023-02-16 WO disclosed
CN-111836841-B Water-soluble copolymer 瓦克化学股份公司 2022-07-29 CN disclosed
CN-114450329-A Film for producing optical film, method for producing optical film, and optical film 株式会社可乐丽 2022-05-06 CN disclosed
EP-0187673-B1 WATER RESISTANT COMPOSITION AND HEAT-SENSITIVE RECORDING SHEET CONTAINING THE SAME KURARAY CO., LTD. (JP) 1991-03-13 EP disclosed
EP-0123927-B1 WATER RESISTANT COMPOSITIONS KURARAY CO., LTD. (JP) 1990-07-25 EP disclosed
EP-0146138-B1 MELT MOLDING MATERIAL KURARAY CO., LTD. (JP) 1988-12-28 EP disclosed
US-4708947-A POLYVINYL ALCOHOL, A CHITOSAN AND AN ALDEHYDE KURARAY CO., LTD. (JP) 1987-11-24 US disclosed
EP-0187673-A2 Water resistant composition and heat-sensitive recording sheet containing the same KURARAY CO., LTD. (JP) 1986-07-16 EP disclosed
US-4567221-A DEFOGGING AGENTS, SOLIDIFICATION OF SOILS KURARAY CO., LTD. (JP) 1986-01-28 US disclosed
EP-0123927-A2 Water resistant compositions KURARAY CO., LTD. (JP) 1984-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179251-A1 COMPOSITION COMPRISING METHACRYLAMIDE GROUP-CONTAINING ORGANIC SILICON COMPOUND AND ARTICLE SURFACE-TREATED WITH SAID COMPOSITION CHRM1, CHRM2, CD68 ALDH1A1 2154/4885TGFBR1 1132/4885THRB 1858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.