SCHEMBL6066974

SCHEMBL6066974

C=C(C)C(=O)NC[Si](C)(C)OC

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TGFBR1 P36897 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6066883 0.84 ALDH1A1 (0.38) ALDH1A1TGFBR1
SCHEMBL23455661 0.82 ALDH1A1 (0.32) ALDH1A1TGFBR1
SCHEMBL4631060 0.82 ALDH1A1 (0.37) ALDH1A1TGFBR1TSHR
SCHEMBL168292 0.82 ALDH1A1 (0.39) ALDH1A1TGFBR1
SCHEMBL6066783 0.81 THRB (0.35) ALDH1A1TGFBR1
SCHEMBL21734383 0.81 ALDH1A1 (0.31) ALDH1A1TGFBR1
SCHEMBL169376 0.79 ALDH1A1 (0.34) ALDH1A1TGFBR1TSHR
SCHEMBL8152798 0.78 TGFBR1 (0.33) TGFBR1
SCHEMBL24024113 0.77 TGFBR1 (0.35) ALDH1A1TGFBR1
SCHEMBL23455658 0.74 ALDH1A1 (0.32) ALDH1A1TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006087079-A1 COMPOSITIONS CURED BY MICHAEL ADDITION REACTION Consortium für elektrochemische Industrie GmbH (DE) 2006-08-24 WO disclosed