SCHEMBL16829784

SCHEMBL16829784

CCCCCC=CCC=CCCCCCCCC(=O)OCCC(O)CC(CCCCCCCC)CCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.57
ALDH1A1 P00352 2/20 0.56
MAPT P10636 1/20 0.56
THRB P10828 1/20 0.56
CNR1 P21554 1/20 0.56
FAAH O00519 4/20 0.56
DGKA P23743 1/20 0.55
LPAR1 Q92633 6/20 0.50
LPAR4 Q99677 3/20 0.50
LPAR2 Q9HBW0 3/20 0.50
LPAR3 Q9UBY5 3/20 0.50
ENPP2 Q13822 2/20 0.50
LPAR5 Q9H1C0 2/20 0.50
CES2 O00748 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LPAR6 P43657 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16829781 1.00 MGLL (0.57) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL16829780 1.00 MGLL (0.57) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL16845021 0.90 MGLL (0.63) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL16829870 0.89 DGKA (0.59) ALDH1A1MAPTDGKALPAR1LPAR4
SCHEMBL12294880 0.87 ALDH1A1 (0.61) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL30457764 0.86 MGLL (0.64) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL30304084 0.86 MGLL (0.64) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL29657524 0.86 MGLL (0.64) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL8607158 0.86 DGKA (0.64) MGLLALDH1A1MAPTTHRBCNR1
SCHEMBL7128696 0.85 MGLL (0.65) MGLLALDH1A1MAPTTHRBCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4019506-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2022-06-29 EP disclosed
EP-3083579-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2022-01-26 EP disclosed
US-11013696-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2021-05-25 US disclosed
US-10426737-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2019-10-01 US disclosed
US-20160317458-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2016-11-03 US disclosed
EP-3083579-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2016-10-26 EP disclosed
WO-2015095346-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2015-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160317458-A1 Lipids and Lipid Compositions for the Delivery of Active Agents SGMS1, PHOSPHO1, LIPA MGLL 46/4885ALDH1A1 1484/4885MAPT 3985/4885
US-10426737-B2 Lipids and lipid compositions for the delivery of active agents SGMS1, PHOSPHO1, LIPA MGLL 46/4885ALDH1A1 1484/4885MAPT 3985/4885
US-11013696-B2 Lipids and lipid compositions for the delivery of active agents PHOSPHO1, SGMS1, LIPA MGLL 48/4885ALDH1A1 1564/4885MAPT 4065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.