Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443114 | 0.84 | ADRB2 (0.68) | ADRB2ABCB11 | |
| SCHEMBL1683034 | 0.84 | ADRB2 (0.59) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL4434958 | 0.84 | ADRB2 (0.67) | ADRB2ABCB11 | |
| SCHEMBL2211009 | 0.84 | ADRB2 (0.67) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL1827610 | 0.83 | ADRB2 (0.66) | ADRB2ABCB11ADRB1DRD2 | |
| SCHEMBL2211014 | 0.82 | ADRB2 (0.65) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL1827166 | 0.81 | ADRB2 (0.63) | ADRB2ABCB11ADRB1DRD2 | |
| Hydrochloric Acid SCHEMBL7852828 | 0.80 | ADRB2 (0.70) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Bromide SCHEMBL1825951 | 0.80 | ADRB2 (0.62) | ADRB2ABCB11ADRB1DRD2 | |
| SCHEMBL8879323 | 0.80 | ADRB2 (0.61) | ADRB2ABCB11ADRB1DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341968-A1 | A BREATH ACTIVATED INHALER | AstraZeneca AB (SE) | 2011-07-13 | — | — | EP | disclosed |
| EP-2334358-A1 | INHALATION DEVICE AND METHOD OF DISPENSING MEDICAMENT | AstraZeneca AB (SE) | 2011-06-22 | — | — | EP | disclosed |
| EP-2303266-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A 4-HYDROXY-2-OXO-2, 3- DIHYDRO-1, 3-BENZOTHIAZOL-7-YL COMPOUND FOR MODULATION OF BETA2-ADRENORECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2011-04-06 | — | — | EP | disclosed |