Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211009 | 0.90 | ADRB2 (0.67) | ADRB2ABCB11 | |
| SCHEMBL2211014 | 0.89 | ADRB2 (0.65) | ADRB2ABCB11 | |
| SCHEMBL4443114 | 0.85 | ADRB2 (0.68) | ADRB2ABCB11 | |
| SCHEMBL1683036 | 0.84 | ADRB2 (0.71) | ADRB2ABCB11 | |
| SCHEMBL1827610 | 0.83 | ADRB2 (0.66) | ADRB2ABCB11 | |
| SCHEMBL2209331 | 0.82 | ADRB2 (0.54) | ADRB2ABCB11 | |
| SCHEMBL1827166 | 0.81 | ADRB2 (0.63) | ADRB2ABCB11 | |
| Bromide SCHEMBL1825951 | 0.81 | ADRB2 (0.62) | ADRB2ABCB11 | |
| SCHEMBL2208928 | 0.81 | ADRB2 (0.59) | ADRB2 | |
| SCHEMBL2209077 | 0.80 | ADRB2 (0.54) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121642-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075026-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |