Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.45 |
| ▸ | DRD3 | P35462 | 7/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683037 | 0.80 | ADRB2 (0.47) | ADRB2ADRB1DRD3 | |
| SCHEMBL1683031 | 0.77 | ADRB2 (0.44) | ADRB2ADRB1DRD3 | |
| SCHEMBL3770650 | 0.72 | ADRB2 (0.61) | ADRB2ADRB1DRD3 | |
| SCHEMBL4554541 | 0.71 | ADRB2 (0.59) | ADRB2ADRB1DRD3 | |
| SCHEMBL4717634 | 0.69 | ADRB2 (0.48) | ADRB2ADRB1DRD3 | |
| SCHEMBL1683040 | 0.69 | ADRB2 (0.50) | ADRB2ADRB1DRD3 | |
| SCHEMBL2210710 | 0.69 | ADRB2 (0.48) | ADRB2ADRB1 | |
| SCHEMBL1683042 | 0.69 | ADRB2 (0.48) | ADRB2ADRB1 | |
| SCHEMBL2212511 | 0.69 | ADRB2 (0.48) | ADRB2ADRB1 | |
| SCHEMBL3770646 | 0.68 | ADRB2 (0.52) | ADRB2ADRB1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303266-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A 4-HYDROXY-2-OXO-2, 3- DIHYDRO-1, 3-BENZOTHIAZOL-7-YL COMPOUND FOR MODULATION OF BETA2-ADRENORECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2011-04-06 | — | — | EP | disclosed |