Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689990 | 0.98 | ACHE (0.62) | ACHELMNASLC6A4DRD2DRD4 | |
| SCHEMBL29567963 | 0.98 | ACHE (0.62) | ACHELMNASLC6A4DRD2DRD4 | |
| SCHEMBL1020430 | 0.98 | ACHE (0.62) | ACHELMNASLC6A4DRD2DRD4 | |
| Bromide SCHEMBL9067059 | 0.97 | ACHE (0.60) | ACHELMNASLC6A4DRD2DRD4 | |
| SCHEMBL4160738 | 0.89 | LMNA (0.53) | ACHELMNASLC6A4DRD2DRD4 | |
| SCHEMBL4557182 | 0.84 | LMNA (0.54) | ACHELMNASLC6A4SIGMAR1HTR6 | |
| SCHEMBL3921135 | 0.82 | ACHE (0.68) | ACHELMNADRD2DRD4DRD3 | |
| SCHEMBL31392633 | 0.82 | ACHE (0.68) | ACHEDRD2DRD4DRD3TSHR | |
| SCHEMBL2378007 | 0.82 | TDP1 (0.55) | LMNASLC6A4SIGMAR1TSHRHTR6 | |
| Formic Acid SCHEMBL4823937 | 0.82 | ACHE (0.46) | ACHELMNASLC6A4TSHRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889554-B2 | Excimer forming compounds | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2021-01-12 | — | — | US | disclosed |
| US-10889554-B2 | Excimer forming compounds | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2021-01-12 | — | — | US | disclosed |
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-10-20 | — | — | US | disclosed |
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-10-20 | — | — | US | disclosed |
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-10-20 | — | — | US | disclosed |
| WO-2015089639-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015089639-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889554-B2 | Excimer forming compounds | PHAX, RNMT, POLM | ACHE 4809/4885LMNA 582/4885SLC6A4 2821/4885 |
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | PHAX, RNMT, POLM | ACHE 4809/4885LMNA 582/4885SLC6A4 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.