SCHEMBL1683248

SCHEMBL1683248

OC1CCCCCCCCCCCO1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27835916 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL17685560 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL3422571 1.00
SCHEMBL27835901 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL3420515 1.00
SCHEMBL13519941 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL7218680 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL18501130 1.00
SCHEMBL54593 0.97
SCHEMBL11491558 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940770-B1 NOVEL METHOD FOR PREPARING UNSATURATED FATTY HYDROXYACIDS PIERRE FABRE DERMO COSMÉTIQUE (FR) 2015-11-11 EP disclosed
EP-1937619-B1 NOVEL UNSATURATED FATTY HYDROXY ACID DERIVATIVES AND THE DERMOCOSMETOLOGIC USE THEREOF PIERRE FABRE DERMO COSMÉTIQUE (FR) 2014-10-08 EP disclosed
US-8158811-B2 Unsaturated fatty hydroxy acid derivatives and the dermocosmetologic use thereof PIERRE FABRE DERMO-COSMETIQUE (FR) 2012-04-17 US disclosed
US-7928254-B2 Method for preparing unsaturated fatty hydroxyacids PIERRE FABRE DERMO-COSMETIQUE (FR) 2011-04-19 US disclosed
US-20090238784-A1 Novel Unsaturated Fatty Hydroxy Acid Derivatives and the Dermocosmetologic Use Thereof PIERRE FABRE DERMO-COSMETIQUE (FR) 2009-09-24 US disclosed
US-20080281114-A1 Novel Method for Preparing Unsaturated Fatty Hydroxyacids PIERRE FABRE DERMO-COSMETIQUE (FR) 2008-11-13 US disclosed
EP-1940770-A2 NOVEL METHOD FOR PREPARING UNSATURATED FATTY HYDROXYACIDS Pierre Fabre Dermo-Cosmetique (FR) 2008-07-09 EP disclosed
EP-1937619-A1 NOVEL UNSATURATED FATTY HYDROXY ACID DERIVATIVES AND THE DERMOCOSMETOLOGIC USE THEREOF Pierre Fabre Dermo-Cosmetique (FR) 2008-07-02 EP disclosed
WO-2007045741-A2 NOVEL METHOD FOR PREPARING UNSATURATED FATTY HYDROXYACIDS PIERRE FABRE DERMO COSMETIQUE (FR) 2007-04-26 WO disclosed
WO-2007045693-A1 NOVEL UNSATURATED FATTY HYDROXY ACID DERIVATIVES AND THE DERMOCOSMETOLOGIC USE THEREOF PIERRE FABRE DERMO-COSMETIQUE (FR) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090238784-A1 Novel Unsaturated Fatty Hydroxy Acid Derivatives and the Dermocosmetologic Use Thereof ELOVL3, FFAR3, FASN TSHR 1800/4885NOS2 1763/4885
US-20080281114-A1 Novel Method for Preparing Unsaturated Fatty Hydroxyacids FASN, ELOVL1, ELOVL3 TSHR 3172/4885NOS2 2197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.