SCHEMBL7218680

SCHEMBL7218680

OC1CCCCCCCO1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683248 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL27835916 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL17685560 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL3422571 1.00
SCHEMBL27835901 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL3420515 1.00
SCHEMBL13519941 1.00 TSHR (0.35) TSHRNOS2
SCHEMBL18501130 1.00
SCHEMBL54593 0.97
SCHEMBL11491558 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940770-B1 NOVEL METHOD FOR PREPARING UNSATURATED FATTY HYDROXYACIDS PIERRE FABRE DERMO COSMÉTIQUE (FR) 2015-11-11 EP disclosed
US-20140135342-A1 PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2014-05-15 US disclosed
US-7928254-B2 Method for preparing unsaturated fatty hydroxyacids PIERRE FABRE DERMO-COSMETIQUE (FR) 2011-04-19 US disclosed
US-7928254-B2 Method for preparing unsaturated fatty hydroxyacids PIERRE FABRE DERMO-COSMETIQUE (FR) 2011-04-19 US disclosed
US-20080281114-A1 Novel Method for Preparing Unsaturated Fatty Hydroxyacids PIERRE FABRE DERMO-COSMETIQUE (FR) 2008-11-13 US disclosed
US-20080281114-A1 Novel Method for Preparing Unsaturated Fatty Hydroxyacids PIERRE FABRE DERMO-COSMETIQUE (FR) 2008-11-13 US disclosed
WO-2007045741-A2 NOVEL METHOD FOR PREPARING UNSATURATED FATTY HYDROXYACIDS PIERRE FABRE DERMO COSMETIQUE (FR) 2007-04-26 WO disclosed
EP-1370358-A1 CATALYST FOR PRODUCING BOTH END-HYDROXYL GROUP-TERMINATED DIOLS, PROCESS FOR PRODUCING THE CATALYST, PROCESS FOR PRODUCING THE DIOLS BY USING THE CATALYST, AND BOTH END-HYDROXYL GROUP-TERMINATED DIOLS OBTAINED BY THE PROCESS Showa Denko K.K. (JP) 2003-12-17 EP disclosed
WO-2002076610-A1 CATALYST FOR PRODUCING BOTH END-HYDROXYL GROUP-TERMINATED DIOLS, PROCESS FOR PRODUCING THE CATALYST, PROCESS FOR PRODUCING THE DIOLS BY USING THE CATALYST, AND BOTH END-HYDROXYL GROUP-TERMINATED DIOLS OBTAINED BY THE PROCESS SHOWA DENKO K. K. (JP) 2002-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135342-A1 PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS PREP, PEPD, DNPEP TSHR 4728/4885NOS2 1644/4885
US-20080281114-A1 Novel Method for Preparing Unsaturated Fatty Hydroxyacids FASN, ELOVL1, ELOVL3 TSHR 3172/4885NOS2 2197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.