Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15336426 | 0.86 | KMT2A (0.49) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL22722199 | 0.84 | KMT2A (0.59) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17875396 | 0.78 | KMT2A (0.63) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL19786485 | 0.77 | KMT2A (0.67) | KMT2AMEN1KDM4EALDH1A1ITPR1 | |
| SCHEMBL12177611 | 0.77 | ALDH1A1 (0.48) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24425463 | 0.76 | KMT2A (0.65) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| Methyl Alcohol SCHEMBL28963160 | 0.76 | KMT2A (0.65) | KMT2AMEN1KDM4EALDH1A1ITPR1 | |
| SCHEMBL1714410 | 0.76 | KMT2A (0.68) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6282093 | 0.76 | KMT2A (0.68) | KMT2AMEN1KDM4EALDH1A1ITPR1 | |
| SCHEMBL29369373 | 0.76 | KMT2A (0.68) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187112-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-06-24 | — | — | US | disclosed |
| US-10953105-B2 | Immunostimulatory compositions and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-23 | — | — | US | disclosed |
| US-20190015522-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-01-17 | — | — | US | disclosed |
| US-10029016-B2 | Immunostimulatory compositions and methods of use thereof | MASSACHUSETTS INSITUTE OF TECHNOLOGY (US) | 2018-07-24 | — | — | US | disclosed |
| US-20160095936-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-04-07 | — | — | US | disclosed |
| US-9107904-B2 | Immunostimulatory compositions and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-08-18 | — | — | US | disclosed |
| US-20130295129-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-11-07 | — | — | US | disclosed |
| US-20120087949-A1 | OLIGONUCLEOTIDE MICELLES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-04-12 | — | — | US | disclosed |
| WO-2010071852-A2 | OLIGONUCLEOTIDE MICELLES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953105-B2 | Immunostimulatory compositions and methods of use thereof | PHOSPHO1, MYD88, CD47 | KMT2A 4569/4885MEN1 3117/4885KDM4E 4553/4885 |
| US-10029016-B2 | Immunostimulatory compositions and methods of use thereof | PHOSPHO1, MYD88, CD47 | KMT2A 4569/4885MEN1 3117/4885KDM4E 4553/4885 |
| US-20130295129-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | PHOSPHO1, MYD88, CD47 | KMT2A 4569/4885MEN1 3117/4885KDM4E 4553/4885 |
| US-20120087949-A1 | OLIGONUCLEOTIDE MICELLES | POLRMT, MICA, HLA-DRB1 | KMT2A 3744/4885MEN1 399/4885KDM4E 4769/4885 |
| US-20210187112-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | PHOSPHO1, MYD88, CD47 | KMT2A 4569/4885MEN1 3117/4885KDM4E 4553/4885 |
| US-20160095936-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | PHOSPHO1, MYD88, CD47 | KMT2A 4569/4885MEN1 3117/4885KDM4E 4553/4885 |
| US-20190015522-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | PHOSPHO1, MYD88, CD47 | KMT2A 4569/4885MEN1 3117/4885KDM4E 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.