Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273884 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL38666469 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL5329998 | 0.84 | MAPT (0.55) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL38666623 | 0.80 | MAPT (0.51) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL5330002 | 0.79 | MAPT (0.50) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL6690449 | 0.79 | SMN1; SMN2 (0.43) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL6200618 | 0.79 | SMN1; SMN2 (0.50) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL6994179 | 0.76 | MEN1 (0.49) | MAPTCYP1A2GAASMN1; SMN2PKM | |
| SCHEMBL6443970 | 0.76 | SMN1; SMN2 (0.58) | MAPTALDH1A1MAPK1NPSR1CYP1A2 | |
| SCHEMBL25170908 | 0.74 | PKM (0.47) | MAPTALDH1A1MAPK1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083598-A1 | GLUCOSE TRANSPORT INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091428-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |