Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273884 | 0.84 | ALDH1A1 (0.55) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL5329998 | 0.81 | MAPT (0.55) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL38666469 | 0.81 | ALDH1A1 (0.55) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL16833262 | 0.79 | MAPT (0.53) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL38666623 | 0.77 | MAPT (0.51) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL25170908 | 0.74 | PKM (0.47) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL2386652 | 0.74 | PKM (0.66) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL18282576 | 0.72 | PKM (0.48) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL9202274 | 0.71 | PKM (0.47) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL8144751 | 0.71 | PKM (0.56) | MAPTMAPK1ALDH1A1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011647-A2 | INHIBITORS OF MITOTIC KINESIN KSP | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |