SCHEMBL168345

SCHEMBL168345

[CH]1c2ccccc2Sc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.56
BCHE P06276 5/20 0.43
NOX1 Q9Y5S8 3/20 0.43
GAA P10253 3/20 0.43
MAPT P10636 3/20 0.43
ACHE P22303 3/20 0.43
MAOA P21397 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
CNR1 P21554 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
HTR2C P28335 1/20 0.43
PTGS2 P35354 1/20 0.43
SNCA P37840 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742301 0.81 TRPA1 (0.50) TRPA1BCHENOX1GAAMAPT
SCHEMBL10558596 0.80 ACHE (0.50) TRPA1BCHENOX1MAPTACHE
SCHEMBL5261722 0.78 TRPA1 (0.43) TRPA1BCHENOX1GAAMAPT
SCHEMBL21629348 0.75 BCHE (0.56) TRPA1BCHENOX1GAAMAPT
Thianthrene SCHEMBL29392368 0.75 BCHE (0.56) TRPA1BCHENOX1GAAMAPT
SCHEMBL30823 0.75
Thianthrene SCHEMBL7786 0.75 BCHE (0.56) TRPA1BCHENOX1GAAMAPT
SCHEMBL1695335 0.75 TRPA1 (0.41) TRPA1BCHENOX1GAAMAPT
SCHEMBL6977130 0.75 TRPA1 (0.41) TRPA1BCHENOX1GAAMAPT
Dibenzo[B,F][1,4]Thiazepine SCHEMBL696578 0.73 TRPA1 (1.00) TRPA1BCHENOX1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1581 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399199-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Reuter Chemische Apparatebau e.K. (DE) 2024-07-17 EP claimed
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP claimed
WO-2024140063-A1 THIOXANTHENE SULFONIUM SALT PHOTOINITIATOR AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 常州强力电子新材料股份有限公司 2024-07-04 WO claimed
WO-2024140062-A1 THIOXANTHENIUM SALT PHOTOINITIATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 常州强力电子新材料股份有限公司 2024-07-04 WO claimed
CN-118271280-A Thioxanthene sulfonium salt photoinitiator and preparation method and application thereof 常州强力电子新材料股份有限公司 2024-07-02 CN claimed
CN-118271281-A Thioxanthene sulfonium salt photoinitiator and preparation method and application thereof 常州强力电子新材料股份有限公司 2024-07-02 CN claimed
CN-118251380-A Spiro- (indan-fluorene) compounds and their use in organic electronic devices 多蒂肯独家合成控股公司 2024-06-25 CN claimed
CN-118043298-A (Hetero) aryl-substituted bisphenol compound and thermoplastic resin 罗伊特化学仪器制造公司 2024-05-14 CN claimed
WO-2024077223-A1 PROTEIN PHOSPHATASE 2A ACTIVATORS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-11 WO claimed
CN-116948152-A Asymmetric imide polymer and preparation method and application thereof 徐州工程学院 2023-10-27 CN claimed
US-4824612-A REACTING A SULFONYL CHLORIDE TO FORM AROMATIC KETONES AND SULFINIC ACIDS CIBA-GEIGY CORPORATION (US) 1989-04-25 US claimed
US-4366309-A MACROLACTONES SCHERING CORPORATION (US) 1982-12-28 US claimed
EP-0033433-A1 Macrolide antibiotics, process for their preparation, inter alia by fermentation, and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1981-08-12 EP claimed
US-4140681-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1979-02-20 US claimed
US-4131673-A INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1978-12-26 US claimed
US-4125604-A PEPTIDES, ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-11-14 US claimed
US-4116665-A Method of regulating the growth of aquatic weeds with pyridine derivatives ELI LILLY AND COMPANY (US) 1978-09-26 US claimed
US-4101653-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4093712-A ANTITHROMBOGENIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-06 US claimed
US-4066773-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US claimed