Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16834588 | 1.00 | FTO (0.52) | FTOEGLN2EGLN1TLR7CA2 | |
| SCHEMBL8882571 | 0.90 | FTO (0.51) | FTOEGLN2EGLN1TLR7CA2 | |
| SCHEMBL8779226 | 0.90 | FTO (0.51) | FTOEGLN2EGLN1TLR7CA2 | |
| SCHEMBL8779215 | 0.90 | FTO (0.51) | FTOEGLN2EGLN1TLR7CA2 | |
| SCHEMBL16834813 | 0.85 | FTO (0.55) | FTOEGLN2EGLN1TLR7CA2 | |
| SCHEMBL1921280 | 0.85 | FTO (0.55) | FTOEGLN2EGLN1TLR7CA2 | |
| SCHEMBL14284378 | 0.79 | ALDH1A1 (0.61) | FTOEGLN2LMNAGAAHPGD | |
| SCHEMBL16834675 | 0.79 | FTO (0.54) | FTOEGLN2CA2CA1FPR2 | |
| SCHEMBL16834681 | 0.79 | FTO (0.54) | FTOEGLN2CA2CA1FPR2 | |
| SCHEMBL1921253 | 0.77 | FTO (0.49) | FTOEGLN2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015092412-A1 | CHEMICAL COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-06-25 | — | — | WO | claimed |
| WO-2015092412-A1 | CHEMICAL COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015092412-A1 | CHEMICAL COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-06-25 | — | — | WO | disclosed |