Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.51 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779226 | 1.00 | FTO (0.51) | FTOEGLN2CA2CA1TLR7 | |
| SCHEMBL8882571 | 1.00 | FTO (0.51) | FTOEGLN2CA2CA1TLR7 | |
| SCHEMBL16834588 | 0.90 | FTO (0.52) | FTOEGLN2CA2CA1TLR7 | |
| SCHEMBL16834752 | 0.90 | FTO (0.52) | FTOEGLN2CA2CA1TLR7 | |
| SCHEMBL1921280 | 0.84 | FTO (0.55) | FTOEGLN2CA2CA1TLR7 | |
| SCHEMBL16834813 | 0.84 | FTO (0.55) | FTOEGLN2CA2CA1TLR7 | |
| SCHEMBL14284378 | 0.78 | ALDH1A1 (0.61) | FTOEGLN2 | |
| SCHEMBL16834675 | 0.78 | FTO (0.54) | FTOEGLN2CA2CA1MME | |
| SCHEMBL16834681 | 0.78 | FTO (0.54) | FTOEGLN2CA2CA1MME | |
| SCHEMBL27883403 | 0.77 | KDM4E (0.54) | CA2CA1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | claimed |