Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836724 | 1.00 | MMP13 (0.34) | MMP13ADAM17 | |
| SCHEMBL18421794 | 0.85 | HTR7 (0.39) | — | |
| SCHEMBL18422325 | 0.84 | AR (0.36) | — | |
| SCHEMBL18422324 | 0.84 | AR (0.36) | — | |
| SCHEMBL18422749 | 0.84 | — | — | |
| SCHEMBL18422746 | 0.84 | — | — | |
| SCHEMBL16836697 | 0.82 | MMP1 (0.46) | MMP13ADAM17 | |
| SCHEMBL18423138 | 0.82 | MMP1 (0.46) | MMP13ADAM17 | |
| SCHEMBL16836698 | 0.82 | MMP1 (0.46) | MMP13ADAM17 | |
| SCHEMBL16836940 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083567-A1 | ANTIBACTERIAL 1H-INDAZOLE AND 1H-INDOLE DERIVATIVES | Actelion Pharmaceuticals Ltd (CH) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091741-A1 | ANTIBACTERIAL 1H-INDAZOLE AND 1H-INDOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2015-06-25 | — | — | WO | disclosed |