Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.64 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.64 |
| ▸ | HTR3B | O95264 | 2/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.64 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.64 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.64 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.64 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885564 | 0.81 | HTR3A (0.69) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL6892488 | 0.81 | HTR3A (0.69) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL2192432 | 0.81 | CHRNB2 (0.64) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL6885570 | 0.81 | CHRNB2 (0.64) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL16838597 | 0.80 | HTR3A (0.60) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL6892215 | 0.80 | CHRNA3 (0.71) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL6886540 | 0.80 | CHRNA3 (0.71) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL6888233 | 0.78 | HTR3A (0.69) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL2190762 | 0.78 | CHRNA7 (0.69) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL6891582 | 0.78 | HTR3A (0.69) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062042-B2 | Nicotinic acetylcholine receptor modulators | ASTRAEA THERAPEUTICS, LLC (US) | 2015-06-23 | — | — | US | disclosed |