Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 7/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16839762 | 0.84 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1CYP2D6CYP1A2HDAC1 | |
| SCHEMBL9524914 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL16839741 | 0.80 | LTA4H (0.48) | SMN1; SMN2ALDH1A1KDM4ECYP2D6CYP1A2 | |
| SCHEMBL16839868 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16839657 | 0.78 | KDM4E (0.42) | F2F10PRSS1CDK2CCNE1 | |
| SCHEMBL16839851 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL16839777 | 0.76 | MEN1 (0.52) | SMN1; SMN2ALDH1A1KDM4EEPHX2MEN1 | |
| SCHEMBL334806 | 0.76 | LMNA (0.51) | SMN1; SMN2KDM4EL3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL16839629 | 0.75 | CYP2D6 (0.46) | SMN1; SMN2ALDH1A1KDM4ECYP2D6CYP1A2 | |
| SCHEMBL1773404 | 0.75 | CYP1A2 (0.49) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422240-B2 | Partially saturated nitrogen-containing heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2016-08-23 | — | — | US | disclosed |
| US-20150175541-A1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175541-A1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | EGLN2, EGLN3, EGLN1 | SMN1; SMN2 2832/4885F2 2370/4885F10 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.