Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.72 |
| ▸ | LTA4H | P09960 | 1/20 | 0.68 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | CTSC | P53634 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186466 | 0.87 | LTA4H (0.69) | SLC15A1LTA4HALPIPKMPTGS1 | |
| SCHEMBL11124563 | 0.84 | SLC15A1 (1.00) | SLC15A1LTA4HALPIPKMPTGS1 | |
| SCHEMBL11124557 | 0.84 | SLC15A1 (1.00) | SLC15A1LTA4HALPIPKMPTGS1 | |
| SCHEMBL11124554 | 0.84 | SLC15A1 (1.00) | SLC15A1LTA4HALPIPKMPTGS1 | |
| SCHEMBL12433005 | 0.82 | SLC15A1 (0.72) | SLC15A1LTA4HALPIPKMPTGS1 | |
| SCHEMBL20630639 | 0.82 | SLC15A1 (0.72) | SLC15A1LTA4HALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL11123747 | 0.82 | SLC15A1 (0.96) | SLC15A1LTA4HALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL11123750 | 0.82 | SLC15A1 (0.96) | SLC15A1LTA4HALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL11123752 | 0.82 | SLC15A1 (0.96) | SLC15A1LTA4HALPIPKMPTGS1 | |
| SCHEMBL15244990 | 0.82 | SLC15A1 (0.72) | SLC15A1LTA4HALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105451716-A | Heat stable dry powder pharmaceutical compositions and methods | MANNKIND CORP | 2016-03-30 | — | — | CN | disclosed |
| US-9000036-B2 | Compositions and methods for targeting of treating neoplasms | Yu, Baofa (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140037695-A1 | COMPOSITIONS AND METHODS FOR TARGETING OF TREATING NEOPLASMS | YU, BAOFA | 2014-02-06 | — | — | US | disclosed |
| US-8501243-B2 | Targeting cancer therapy combination | YU, BAOFA | 2013-08-06 | — | — | US | disclosed |
| US-7927612-B2 | Mixture of an oxidizing agent or a reducing agent, a protein denaturing agent, and a hapten; can be used with other anticancer treatments such as radiotherapy, chemotherapy; coagulate tumors and enhance inflammatory response against systemic tumors at multiple sites | Yu, Baofa (US) | 2011-04-19 | — | — | US | disclosed |
| CN-101951985-A | Device for closing atrial septal defects | MICHAEL AFREMOV | 2011-01-19 | — | — | CN | disclosed |
| US-20100104660-A1 | COMPOSITION AND METHOD FOR TREATING TUMOR | YU, BAOFA | 2010-04-29 | — | — | US | disclosed |
| US-20050118187-A1 | Combinations and methods for treating neoplasms | YU, BAOFA | 2005-06-02 | — | — | US | disclosed |
| US-6811788-B2 | ONE OR MORE HAPTENS AND COAGULATION AGENTS OR TREATMENTS, ALONE OR IN COMBINATION WITH OTHER ANTI-NEOPLASTIC AGENTS OR TREATMENTS | Yu, Baofa | 2004-11-02 | — | — | US | disclosed |
| CN-1186502-A | Compositions and methods for inhibiting thrombogenesis | HAMILTON CIVIC HOSPITALS RES (CA) | 1998-07-01 | — | — | CN | disclosed |