SCHEMBL11124563

SCHEMBL11124563

N[C@@H](Cc1ccccc1)C(=O)CCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SLC15A1 P46059 2/20 1.00
▸ LTA4H P09960 1/20 0.81
▸ ALPI P09923 1/20 0.63
▸ PKM P14618 1/20 0.63
▸ PTGS1 P23219 1/20 0.63
▸ XIAP P98170 1/20 0.63
▸ SLC7A5 Q01650 1/20 0.63
▸ KEAP1 Q14145 1/20 0.53
▸ ACE P12821 1/20 0.52
▸ CPA3 P15088 1/20 0.51
▸ SLC1A3 P43003 2/20 0.50
▸ SLC1A2 P43004 2/20 0.50
▸ SLC1A1 P43005 2/20 0.50
▸ CTSC P53634 1/20 0.50
▸ FFAR1 O14842 1/20 0.50
▸ HDAC8 Q9BY41 2/20 0.49
▸ CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11124554 1.00 SLC15A1 (1.00) SLC15A1LTA4HALPIPKMPTGS1
SCHEMBL11124557 1.00 SLC15A1 (1.00) SLC15A1LTA4HALPIPKMPTGS1
Hydrochloric Acid SCHEMBL11123750 0.98 SLC15A1 (0.96) SLC15A1LTA4HALPIPKMPTGS1
Hydrochloric Acid SCHEMBL11123747 0.98 SLC15A1 (0.96) SLC15A1LTA4HALPIPKMPTGS1
Hydrochloric Acid SCHEMBL11123752 0.98 SLC15A1 (0.96) SLC15A1LTA4HALPIPKMPTGS1
Hydrochloric Acid SCHEMBL9265067 0.88 LTA4H (0.97) SLC15A1LTA4HALPIPKMPTGS1
Phenylalanine SCHEMBL542311 0.87 SLC7A5 (0.85) SLC15A1LTA4HALPIPKMPTGS1
Dl-Phenylalanine SCHEMBL542310 0.87 SLC7A5 (0.85) SLC15A1LTA4HALPIPKMPTGS1
SCHEMBL1684068 0.84 SLC15A1 (0.72) SLC15A1LTA4HALPIPKMPTGS1
SCHEMBL20630639 0.84 SLC15A1 (0.72) SLC15A1LTA4HALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230046194-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-02-16 — — US disclosed
US-10745705-B2 Ribosome-mediated incorporation of peptides and peptidomimetics ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-08-18 — — US disclosed
US-20200172575-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2020-06-04 — — US disclosed
EP-3650464-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND XDCExplorer (Shanghai) Co., Ltd. (CN) 2020-05-13 — — EP disclosed
WO-2019007383-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND 凯惠科技发展(上海)有限公司 2019-01-10 — — WO disclosed
US-20180002709-A1 RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-01-04 — — US disclosed
WO-2016118877-A1 RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-07-28 — — WO disclosed
EP-0045161-B1 AMIDES OF 4-OXO-5-AMIDOHEXANOIC ACID DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-03-14 — — EP disclosed
EP-0045161-A1 Amides of 4-oxo-5-amidohexanoic acid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-02-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180002709-A1 RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS NPEPPS, DNPEP, AARS1 SLC15A1 3525/4885LTA4H 4369/4885ALPI 4152/4885
US-20230046194-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics NPEPPS, DNPEP, AARS1 SLC15A1 3525/4885LTA4H 4369/4885ALPI 4152/4885
US-10745705-B2 Ribosome-mediated incorporation of peptides and peptidomimetics NPEPPS, DNPEP, AARS1 SLC15A1 3525/4885LTA4H 4369/4885ALPI 4152/4885
US-20200172575-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND KISS1R, VIP, NPY1R SLC15A1 544/4885LTA4H 2279/4885ALPI 2329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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