SCHEMBL16841

SCHEMBL16841

Brc1ccc(Br)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL27841183 0.92 ALDH1A1 (0.46)
Cyanide SCHEMBL28300166 0.92 ALDH1A1 (0.41)
Formic Acid SCHEMBL28300164 0.85 ALDH1A1 (0.47)
Hexane SCHEMBL28095543 0.83 RAB9A (0.49)
SCHEMBL16520501 0.80 NPC1 (0.54)
SCHEMBL9035328 0.78 ALDH1A1 (0.55)
SCHEMBL8347881 0.77
SCHEMBL40864 0.75 KDM4E (0.46)
SCHEMBL130166 0.71
SCHEMBL3928499 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6278 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344514-A Synthesis of functional porous organic polymer and application of functional porous organic polymer in catalyzing carbon dioxide cycloaddition reaction 浙江理工大学嵊州创新研究院有限公司 2024-07-16 CN claimed
CN-118166397-A Preparation of polymer carbon fiber photo-anode and application of polymer carbon fiber photo-anode in photo-decomposition of water 福州大学 2024-06-11 CN claimed
CN-118027070-A Triazolopyridine bromodomain protein 4 small molecule inhibitor and preparation method and application thereof 中国药科大学 2024-05-14 CN claimed
CN-115010656-B Preparation method of 5-acetyl-2-bromopyridine 苏州昊帆生物股份有限公司 2024-04-26 CN claimed
CN-117820212-A Production process of 5-bromo-2- (methylthio) pyridine 浙江辰阳化工有限公司 2024-04-05 CN claimed
CN-113717166-B Synthesis method of pramipexole 杭州科巢生物科技有限公司 2024-04-05 CN claimed
CN-117777012-A 2, 5-dimethoxy pyridine and preparation method thereof 常熟泓德生物科技有限公司 2024-03-29 CN claimed
CN-115304544-B Synthesis method of 5-bromo-2- (methylamino) pyridine 童航 2024-02-09 CN claimed
CN-115433122-B Preparation method of 6-fluoro nicotinic acid 大连双硼医药化工有限公司 2024-01-30 CN claimed
CN-117362356-A Tricyclic metal iridium (III) complex containing viologen units, and preparation method and application thereof 南京邮电大学 2024-01-09 CN claimed
EP-1736466-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents The University of North Carolina at Chapel Hill (US) 2006-12-27 EP claimed
US-6706885-B2 HYDROGENATION OF PROTECTED 2,5-DI-(3'-AMINOPROP-1-YNYL) PYRIDINES AND DEPROTECTING TO FORM 2,5-DI-(3'-AMINOPROPYL)-PYRIDINES MERCK & CO., INC. 2004-03-16 US claimed
US-20030004353-A1 Process for preparing integrin antagonist intermediates MERCK SHARP & DOHME CORP. 2003-01-02 US claimed
US-6420565-B2 REACTING BUTYLLITHIUM WITH 2,5-DIHALOPYRIDINE IN A NON-COORDINATING SOLVENT MERCK & CO., INC. 2002-07-16 US claimed
US-20020016470-A1 Process for making 2, 5-Substituted pyridine MERCK FROSST CANADA LTD. (CA) 2002-02-07 US claimed
US-6262268-B1 REACTING 2,5-DI(3-PROPYLAMINO)PYRIDINE WITH BASE IN SOLVENT TO FORM 3-(5,6,7,8-TETRAHYDRO-(1,8)-NAPHTHYRIDIN-2-YL)-PROPYLAMINE AND ISOLATING PRODUCT MERCK & CO., INC. 2001-07-17 US claimed
US-6176909-B1 IN POLYMERIC BINDER XEROX CORPORATION 2001-01-23 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed