Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 5/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805912 | 0.85 | GUCY1A1 (0.33) | RIPK1KMT2AGUCY1A1GUCY1B1KCNH2 | |
| SCHEMBL1684143 | 0.73 | RIPK1 (0.42) | RIPK1KMT2AMPOCYP3A4CYP2D6 | |
| SCHEMBL1684138 | 0.69 | MPO (0.37) | RIPK1KMT2AMPOCYP3A4CYP2D6 | |
| SCHEMBL6856773 | 0.67 | RIPK1 (0.53) | RIPK1KMT2ASLC6A4 | |
| SCHEMBL2951355 | 0.67 | FSCN1 (0.38) | RIPK1KCNH2PTGDR2 | |
| SCHEMBL1684121 | 0.65 | RIPK1 (0.46) | RIPK1MPOCYP3A4SLC6A4 | |
| SCHEMBL1684177 | 0.64 | RIPK1 (0.45) | RIPK1CYP3A4SLC6A4 | |
| SCHEMBL1684122 | 0.63 | RIPK1 (0.43) | RIPK1MPOSLC6A4 | |
| SCHEMBL1241322 | 0.61 | GPR84 (0.67) | GPR84KMT2AMPOCYP3A4CYP2D6 | |
| SCHEMBL3216581 | 0.61 | MPO (0.72) | GPR84KMT2AMPOCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |