SCHEMBL1684281

SCHEMBL1684281

COP(=S)(OC)Oc1cc(C)ccc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
ALDH1A1 P00352 11/20 0.49
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPK1 P28482 2/20 0.49
TP53 P04637 2/20 0.49
THRB P10828 1/20 0.49
HSD17B10 Q99714 1/20 0.49
PKM P14618 1/20 0.47
MAPT P10636 1/20 0.46
S1PR4 O95977 1/20 0.43
KMT2A Q03164 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 1/20 0.43
KDM4E B2RXH2 4/20 0.42
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29790901 1.00 CYP3A4 (0.50) CYP3A4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL9324968 0.88 TSHR (0.47) CYP3A4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL29776928 0.84 ALDH1A1 (0.52) CYP3A4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL3428898 0.83 TSHR (0.51) CYP3A4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL7775360 0.81 TSHR (0.56) CYP3A4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL4370481 0.80 ALDH1A1 (0.61) CYP3A4ALDH1A1LMNASMN1; SMN2MAPK1
SCHEMBL425259 0.79 TSHR (0.62) CYP3A4TSHRALDH1A1LMNAMAPK1
Lithium Ion SCHEMBL8330357 0.78 TSHR (0.53) CYP3A4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL10907764 0.76 CYP3A4 (0.44) CYP3A4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL11046676 0.76 ALDH1A1 (0.43) CYP3A4TSHRALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449975-B1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1997-04-23 EP claimed
EP-0765120-A1 SYNERGISTIC COMPOSITION Novartis AG (CH) 1997-04-02 EP claimed
EP-0736252-A2 Synergistic compositions with diafenthiuron CIBA-GEIGY AG (CH) 1996-10-09 EP claimed
WO-1995033380-A1 SYNERGISTIC COMPOSITION CIBA-GEIGY AG (CH) 1995-12-14 WO claimed
EP-0431361-B1 Use of stabilizers for agrochemical compositions BAYER AGROCHEM KK (JP) 1994-02-23 EP claimed
EP-0431362-B1 Stabilized agrochemical compositions BAYER AGROCHEM KK (JP) 1993-11-03 EP claimed
EP-0431361-A1 Use of stabilizers for agrochemical compositions NIHON BAYER AGROCHEM K.K. (JP) 1991-06-12 EP claimed
EP-0431362-A1 Stabilized agrochemical compositions NIHON BAYER AGROCHEM K.K. (JP) 1991-06-12 EP claimed
EP-0017738-B1 AN INSECTICIDAL AND MITICIDAL COMPOSITION WHICH CONTAINS A CARBAMATE AND AN ORGANIC PHOSPHORUS COMPOUND, AND A METHOD OF CONTROLLING INSECTS AND MITES THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-08 EP claimed
JP-56010102-A None JP disclosed
JP-59039810-A None JP disclosed
US-12414560-B2 Pesticidal compositions and related methods CJB APPLIED TECHNOLOGIES, LLC (US) 2025-09-16 US disclosed
US-20230082819-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB APPLIED TECH LLC (US) 2023-03-16 US disclosed
EP-4145995-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB Applied Technologies, LLC (US) 2023-03-15 EP disclosed
US-4349554-A Method of using carbostyril derivatives as plant fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-09-14 US disclosed
US-4339443-A Compounds and compositions FBC LIMITED (GB) 1982-07-13 US disclosed
US-4309559-A PLANT GROWTH REGULATORS AND ESPECIALLY FUNGICIDES OR HERBICIDES FBC LIMITED (GB) 1982-01-05 US disclosed
JP-S5610102-A STABILIZED AGRICULTURAL CHEMICAL COMPOSITION KUMIAI CHEM IND CO LTD 1981-02-02 JP disclosed
EP-0017738-A1 An insecticidal and miticidal composition which contains a carbamate and an organic phosphorus compound, and a method of controlling insects and mites therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-10-29 EP disclosed
JP-S05939810-A 0001-01-01 JP disclosed