Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783503 | 0.90 | KDM4E (0.38) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL16783830 | 0.82 | ACHE (0.32) | ALDH1A1MEN1KMT2ASMN1; SMN2ACHE | |
| SCHEMBL16783829 | 0.82 | ACHE (0.32) | ALDH1A1MEN1KMT2ASMN1; SMN2ACHE | |
| SCHEMBL21337721 | 0.79 | CYP1A2 (0.36) | ALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL16806402 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL21337764 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16783653 | 0.75 | MEN1 (0.31) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL16783515 | 0.75 | NPC1 (0.44) | ALDH1A1MEN1KMT2AGAANPSR1 | |
| Hydrochloric Acid SCHEMBL16783779 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL16783734 | 0.75 | KDM4E (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091685-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-06-25 | — | — | WO | disclosed |