Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880003 | 0.85 | RORC (0.70) | RORCELANECNR2MAPT | |
| SCHEMBL8974321 | 0.82 | CNR1 (0.54) | ELANECNR1CNR2MAPT | |
| SCHEMBL25516350 | 0.81 | CA2 (0.51) | CNR1CNR2MAPT | |
| SCHEMBL13005177 | 0.81 | ELANE (0.43) | RORCELANECNR1CNR2MAPT | |
| SCHEMBL176221 | 0.81 | ELANE (0.52) | RORCELANE | |
| SCHEMBL2601862 | 0.77 | BRS3 (0.50) | RORCCNR1CNR2 | |
| SCHEMBL5877921 | 0.76 | MAPT (0.50) | CNR1CNR2MAPT | |
| SCHEMBL16573638 | 0.75 | PLK1 (0.53) | MAPT | |
| SCHEMBL1107149 | 0.74 | CNR2 (0.57) | CNR1CNR2MAPT | |
| SCHEMBL3573740 | 0.74 | CNR1 (0.53) | ELANECNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |