Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213672 | 0.93 | ALDH1A1 (0.42) | CES2LSSEP300HCAR2TSHR | |
| SCHEMBL6553353 | 0.85 | HCAR2 (0.35) | CES2LSSEP300HCAR2TSHR | |
| SCHEMBL5386604 | 0.84 | CES2 (0.50) | CES2EP300HCAR2THRBMEN1 | |
| SCHEMBL5399497 | 0.84 | CES2 (0.50) | CES2EP300HCAR2THRBMEN1 | |
| SCHEMBL5382943 | 0.84 | CES2 (0.50) | CES2EP300HCAR2THRBMEN1 | |
| SCHEMBL25222990 | 0.84 | CES2 (0.50) | CES2EP300HCAR2THRBMEN1 | |
| SCHEMBL7092774 | 0.84 | CES2 (0.50) | CES2EP300HCAR2THRBMEN1 | |
| SCHEMBL7776375 | 0.84 | CES2 (0.50) | CES2LSSHCAR2THRBMEN1 | |
| SCHEMBL5830404 | 0.82 | CES2 (0.47) | CES2EP300HCAR2THRBMEN1 | |
| SCHEMBL22972971 | 0.81 | EP300 (0.50) | CES2EP300THRBMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303940-A1 | BLOCK COPOLYMERS ON THE BASIS OF (METH) ACRYLATE | Henkel AG & Co. KGaA (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010009911-A1 | BLOCK COPOLYMERS ON THE BASIS OF (METH) ACRYLATE | HENKEL AG & CO. KGAA (DE) | 2010-01-28 | — | — | WO | disclosed |