SCHEMBL1685045

SCHEMBL1685045

CC(=O)CCC(=O)OP(=O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.40
SLC15A2 Q16348 1/20 0.40
CA4 P22748 1/20 0.39
TSHR P16473 1/20 0.36
PEPD P12955 1/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
BTN3A1 O00481 1/20 0.31
MAPT P10636 1/20 0.31
ACHE P22303 1/20 0.30
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28977937 0.96 ALDH1A1 (0.43) ALDH1A1LMNASLC15A2CA4TSHR
SCHEMBL285627 0.87 CA4 (0.48) LMNACA4TSHRPEPD
SCHEMBL27473070 0.85 CA4 (0.46) CA4TSHRPEPD
SCHEMBL1643232 0.85 CA4 (0.46) CA4TSHRPEPD
SCHEMBL28977939 0.81 BTN3A1 (0.42) ALDH1A1LMNASLC15A2BTN3A1
SCHEMBL8561065 0.78 LMNA (0.45) LMNASLC15A2CA4TSHRPEPD
Phosphonic Acid SCHEMBL7991199 0.78 CA4 (0.40) CA4TSHRPEPD
SCHEMBL18696078 0.78 MGAM (0.52) ALDH1A1CA4TSHRPEPDMGAM
SCHEMBL60769 0.78 ALDH1A1 (0.52) ALDH1A1LMNACA4TSHRPEPD
SCHEMBL2201756 0.77 TSHR (0.43) CA4TSHRPEPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240352466-A1 APTAMER-siRNA FUSIONS APTERNA LIMITED (GB) 2024-10-24 US disclosed
CN-118006613-A Aptamer-siRNA fusions 艾普特纳有限公司 2024-05-10 CN disclosed
EP-4361271-A2 APTAMER-SIRNA FUSIONS Apterna Limited (GB) 2024-05-01 EP disclosed
US-20240052355-A1 APTAMER-siRNA FUSIONS APTERNA LIMITED (GB) 2024-02-15 US disclosed
US-10801050-B2 Microorganism modified for the assimilation of levulinic acid METABOLIC EXPLORER (FR) 2020-10-13 US disclosed
EP-3365427-B1 MICROORGANISM MODIFIED FOR THE ASSIMILATION OF LEVULINIC ACID METABOLIC EXPLORER SA (FR) 2020-08-19 EP disclosed
US-20180312890-A1 MICROORGANISM MODIFIED FOR THE ASSIMILATION OF LEVULINIC ACID METABOLIC EXPLORER (FR) 2018-11-01 US disclosed
EP-3365427-A1 MICROORGANISM MODIFIED FOR THE ASSIMILATION OF LEVULINIC ACID Metabolic Explorer (FR) 2018-08-29 EP disclosed
WO-2017068385-A1 MICROORGANISM MODIFIED FOR THE ASSIMILATION OF LEVULINIC ACID METABOLIC EXPLORER (FR) 2017-04-27 WO disclosed
EP-2305237-B1 THERAPEUTIC AGENT FOR MALE STERILITY SBI PHARMACEUTICALS CO LTD (JP) 2014-04-30 EP disclosed
CN-102014847-B Dental composition and composite resin KURARAY MEDICAL INC 2013-12-04 CN disclosed
US-8563605-B2 Therapeutic agent for male sterility SBI PHARMACEUTICALS CO., LTD. (JP) 2013-10-22 US disclosed
CN-102083403-B Dental composition and composite resin KURARAY MEDICAL INC 2013-10-09 CN disclosed
CN-102014848-B Dental composition and composite resin KURARAY MEDICAL INC 2013-06-19 CN disclosed
CN-102083403-A Dental composition and composite resin KURARAY MEDICAL INC 2011-06-01 CN disclosed
CN-102014847-A Dental composition and composite resin KURARAY MEDICAL INC 2011-04-13 CN disclosed
CN-102014848-A Dental composition and composite resin KURARAY MEDICAL INC 2011-04-13 CN disclosed
EP-2305237-A1 THERAPEUTIC AGENT FOR MALE STERILITY SBI ALApromo Co., Ltd. (JP) 2011-04-06 EP disclosed
US-20110065787-A1 THERAPEUTIC AGENT FOR MALE STERILITY SBI ALApromo., Ltd. 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052355-A1 APTAMER-siRNA FUSIONS TFRC, CNBP, CEBPZ ALDH1A1 3477/4885LMNA 1586/4885SLC15A2 1374/4885
US-20240352466-A1 APTAMER-siRNA FUSIONS TFRC, CEBPZ, CNBP ALDH1A1 3524/4885LMNA 1671/4885SLC15A2 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.