Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5275073 | 0.97 | DNM1 (0.55) | DNM1CA2CA1MAPK1CYP3A4 | |
| Acetic Acid SCHEMBL329012 | 0.92 | DNM1 (0.55) | DNM1CA2CA1MAPK1CYP3A4 | |
| Oxalic Acid SCHEMBL1052557 | 0.92 | DNM1 (0.55) | DNM1CA2CA1MAPK1CYP3A4 | |
| Bicarbonate SCHEMBL5275078 | 0.92 | DNM1 (0.55) | DNM1CA2CA1MAPK1CYP3A4 | |
| Acetic Acid SCHEMBL123876 | 0.92 | DNM1 (0.55) | DNM1CA2CA1MAPK1CYP3A4 | |
| Bicarbonate SCHEMBL28469661 | 0.90 | DNM1 (0.67) | DNM1CA2CA1NFKB1CES2 | |
| Propionic Acid SCHEMBL6633544 | 0.90 | DNM1 (0.52) | DNM1CA2CA1MAPK1NFKB1 | |
| Acetic Acid SCHEMBL7563930 | 0.90 | DNM1 (0.52) | DNM1CA2CA1MAPK1CYP3A4 | |
| Malonic Acid SCHEMBL5044965 | 0.87 | CA2 (0.50) | DNM1CA2CA1NFKB1 | |
| Acetic Acid SCHEMBL11408206 | 0.87 | DNM1 (0.50) | DNM1CA2CA1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080196626-A1 | High silicon-content resin composition used to form thin film thermosets; form low k dielectric constant materials; hard mask and underlayer materials with anti-reflective properties for photolithography industry | MERCK PATENT GMBH (DE) | 2008-08-21 | — | — | US | claimed |
| US-6844388-B2 | Fluoropolymer compositions containing a nitrogen cure site monomer | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-18 | — | — | US | claimed |
| EP-0703262-B1 | Process for producing aromatic polycarbonate | MITSUBISHI CHEM CORP (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5578694-A | MELT POLYCONDENSATION OF AROMATIC DIOL AND DIARYL CARBONATE; ESTER INTERCHANGE USING PHOSPHONIUM CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-11-26 | — | — | US | claimed |
| EP-0703262-A2 | Process for producing aromatic polycarbonate | Mitsubishi Chemical Corporation (JP) | 1996-03-27 | — | — | EP | claimed |
| EP-4039760-B1 | POLISHING COMPOSITION | FUJIMI INC (JP) | 2026-04-08 | — | — | EP | disclosed |
| CN-114450376-B | Polishing composition | 福吉米株式会社 | 2024-01-05 | — | — | CN | disclosed |
| WO-2023238500-A1 | TREATMENT AGENT FOR CARBON FIBER PRECURSOR, AND CARBON FIBER PRECURSOR | 竹本油脂株式会社 | 2023-12-14 | — | — | WO | disclosed |
| EP-4039760-A1 | POLISHING COMPOSITION | Fujimi Incorporated (JP) | 2022-08-10 | — | — | EP | disclosed |
| CN-114450376-A | Polishing composition | 福吉米株式会社 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021065644-A1 | POLISHING COMPOSITION | 株式会社フジミインコーポレーテッド | 2021-04-08 | — | — | WO | disclosed |
| CN-106946878-B | Bipolar luminescent material which can be processed by environment-friendly solvent and takes alkyl phenanthroline unit as core, and preparation method and application thereof | 华南理工大学 | 2020-09-22 | — | — | CN | disclosed |
| WO-2003106533-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003106149-A1 | METHOD FOR MAKING AN AROMATIC POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-12-24 | — | — | WO | disclosed |
| US-20030232957-A1 | Method for making an aromatic polycarbonate | GENERAL ELECTRIC COMPANY | 2003-12-18 | — | — | US | disclosed |
| US-20020177666-A1 | Fluoropolymer compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2002-11-28 | — | — | US | disclosed |
| WO-2002083756-A1 | FLUOROPOLYMER COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-10-24 | — | — | WO | disclosed |
| EP-0703262-B1 | Process for producing aromatic polycarbonate | MITSUBISHI CHEM CORP (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5578694-A | MELT POLYCONDENSATION OF AROMATIC DIOL AND DIARYL CARBONATE; ESTER INTERCHANGE USING PHOSPHONIUM CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0703262-A2 | Process for producing aromatic polycarbonate | Mitsubishi Chemical Corporation (JP) | 1996-03-27 | — | — | EP | disclosed |