Malonic Acid

Malonic Acid

SCHEMBL5044965

CCCC[P+](CCCC)(CCCC)CCCC.CCCC[P+](CCCC)(CCCC)CCCC.O=C([O-])CC(=O)[O-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.50
DNM1 Q05193 2/20 0.50
CA4 P22748 2/20 0.48
CA1 P00915 5/20 0.46
NFKB1 P19838 1/20 0.44
GPR84 Q9NQS5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL6633544 0.88 DNM1 (0.52) CA2DNM1CA1NFKB1GPR84
Bicarbonate SCHEMBL1685163 0.87 DNM1 (0.57) CA2DNM1CA1NFKB1
Glycolic Acid SCHEMBL27095075 0.86 CA2 (0.50) CA2DNM1CA1NFKB1GPR84
Succinic Acid SCHEMBL899288 0.86 CA2 (0.61) CA2DNM1CA1NFKB1GPR84
Acetic Acid SCHEMBL123876 0.85 DNM1 (0.55) CA2DNM1CA1NFKB1
Acetic Acid SCHEMBL329012 0.85 DNM1 (0.55) CA2DNM1CA1NFKB1
Oxalic Acid SCHEMBL1052557 0.85 DNM1 (0.55) CA2DNM1CA1NFKB1
Bicarbonate SCHEMBL5275073 0.85 DNM1 (0.55) CA2DNM1CA1NFKB1
Bicarbonate SCHEMBL5275078 0.85 DNM1 (0.55) CA2DNM1CA1NFKB1GPR84
Butyric Acid SCHEMBL10765538 0.84 FFAR3 (0.64) CA2DNM1CA1NFKB1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164875-A Preparation method of tubular metal copper phthalocyanine polymer and cyclic carbonate 浙江理工大学 2023-12-05 CN claimed
EP-3990455-A1 PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-05-04 EP claimed
CN-114269744-A Methods for preparing Toll-like receptor modulator compounds 吉利德科学公司 2022-04-01 CN claimed
US-11286257-B2 Processes for preparing toll-like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2022-03-29 US claimed
US-20210017170-A1 PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. 2021-01-21 US claimed
WO-2020264081-A1 PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2020-12-30 WO claimed
EP-3310476-B1 ANTIFOULING OLIGOMERIZATION CATALYST SYSTEMS SAUDI ARABIAN OIL CO (SA) 2019-09-18 EP claimed
US-10246558-B2 Compositions comprising siloxane compounds and methods for using the same MILLIKEN & COMPANY (US) 2019-04-02 US claimed
EP-3458498-A1 COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME Milliken & Company (US) 2019-03-27 EP claimed
WO-2017201035-A1 COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME MILLIKEN & COMPANY (US) 2017-11-23 WO claimed
US-20170335065-A1 COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME MILLIKEN & COMPANY 2017-11-23 US claimed
EP-4743432-A1 PROCESS FOR SELECTIVE ETHYLENE OLIGOMERIZATION WITH ANTIFOULING COMPONENTS Saudi Arabian Oil Company (SA) 2026-05-20 EP disclosed
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
EP-4582181-A1 ANTIFOULING OLIGOMERIZATION CATALYST SYSTEMS Saudi Arabian Oil Company (SA) 2025-07-09 EP disclosed
EP-4257234-B1 ANTIFOULING OLIGOMERIZATION CATALYST SYSTEMS SAUDI ARABIAN OIL CO (SA) 2025-04-09 EP disclosed
WO-2005045895-A2 CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME SACHEM, INC. (US) 2005-05-19 WO disclosed
EP-1417248-A1 METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-05-12 EP disclosed
US-6569985-B2 Multistage; oligomerization using tetraalykyphosphorium catalyst and Group 1a hydroxide catalyst GENERAL ELECTRIC COMPANY 2003-05-27 US disclosed
US-20030065129-A1 Method for making polycarbonate GENERAL ELECTRIC COMPANY 2003-04-03 US disclosed
WO-2003014188-A1 METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds TLR8, MYD88, TLR6 CA2 1648/4885DNM1 1568/4885CA4 3897/4885
US-20210017170-A1 PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS TLR4, TLR3, TLR6 CA2 3480/4885DNM1 2507/4885CA4 4263/4885
US-11286257-B2 Processes for preparing toll-like receptor modulator compounds TLR4, TLR3, TLR6 CA2 3480/4885DNM1 2507/4885CA4 4263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.