Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 13/20 | 0.65 |
| ▸ | AR | P10275 | 11/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12568120 | 1.00 | PGR (0.65) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL13342048 | 0.85 | PGR (0.55) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL10355878 | 0.85 | PGR (0.55) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL14256416 | 0.83 | PGR (0.64) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL18218187 | 0.83 | PGR (0.64) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL11041227 | 0.83 | PGR (0.64) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL14256378 | 0.83 | PGR (0.64) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL14668726 | 0.82 | PGR (0.72) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL13103488 | 0.82 | PGR (0.72) | PGRARNR3C1CHRM2HTR2B | |
| SCHEMBL16852315 | 0.82 | PGR (0.58) | PGRARNR3C1CHRM2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265629-B1 | BISMETHYLENE-17 CARBOLACTONES AND RELATED USES | EVESTRA INC (US) | 2015-06-24 | — | — | EP | disclosed |