Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852390 | 0.99 | CTSL (0.43) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852367 | 0.95 | THRA (0.42) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852382 | 0.95 | THRA (0.42) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852376 | 0.95 | THRA (0.42) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852374 | 0.95 | THRA (0.42) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852370 | 0.95 | CTSL (0.43) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852380 | 0.94 | THRA (0.40) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852430 | 0.94 | THRB (0.40) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852413 | 0.93 | THRA (0.40) | THRATHRBCTSLCTSSCTSK | |
| SCHEMBL16852386 | 0.91 | THRB (0.39) | THRATHRBCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |