Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097091 | 0.87 | PNMT (0.43) | PNMTCD44MAOBHTR1AMEN1 | |
| SCHEMBL18322481 | 0.82 | PNMT (0.41) | PNMTCD44MAOBMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL18706948 | 0.81 | PNMT (0.40) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL18325442 | 0.77 | PNMT (0.50) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL18325548 | 0.77 | PNMT (0.50) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL599314 | 0.76 | CYP19A1 (0.54) | MAOBHTR1ACYP19A1MTNR1AMTNR1B | |
| SCHEMBL18325505 | 0.72 | PNMT (0.46) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL16852800 | 0.70 | GRIA2 (0.36) | HTR1AMTNR1AMTNR1B | |
| SCHEMBL17120414 | 0.68 | MEN1 (0.51) | MEN1CYP3A4CYP2D6KMT2AHTR2C | |
| SCHEMBL17121746 | 0.68 | MEN1 (0.51) | MEN1CYP3A4CYP2D6KMT2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202253-A1 | NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-12-22 | — | — | WO | disclosed |