Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24384353 | 0.91 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1MEN1 | |
| SCHEMBL1685303 | 0.86 | ALDH1A1 (0.53) | ALDH1A1ADRA2BPTGS1TDP1MEN1 | |
| SCHEMBL32674283 | 0.83 | ALDH1A1 (0.58) | ALDH1A1ADRA2BPTGS1TDP1MEN1 | |
| SCHEMBL1803794 | 0.83 | ALDH1A1 (0.58) | ALDH1A1ADRA2BPTGS1TDP1MEN1 | |
| SCHEMBL395260 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ADRA2BPTGS1TDP1MEN1 | |
| SCHEMBL1922106 | 0.79 | ALDH1A1 (0.59) | ALDH1A1ADRA2BPTGS1TDP1MEN1 | |
| SCHEMBL21886372 | 0.79 | KDM4E (0.47) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL13724253 | 0.78 | ALDH1A1 (0.57) | ALDH1A1ADRA2BPTGS1TDP1MEN1 | |
| SCHEMBL21886373 | 0.77 | MEN1 (0.49) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL301996 | 0.76 | CA1 (0.71) | ALDH1A1ADRA2BPTGS1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2174928-B1 | TRANSITION METAL COMPLEX COMPOUND, OLEFIN OLIGOMERIZATION CATALYST CONTAINING THE COMPOUND, AND METHOD FOR PRODUCING OLEFIN OLIGOMER PERFORMED IN THE PRESENCE OF THE CATALYST | MITSUI CHEMICALS INC (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-8258361-B2 | Transition metal complex compounds, olefin oligomerization catalysts including the compounds, and processes for producing olefin oligomers using the catalysts | MITSUI CHEMICALS, INC. (JP) | 2012-09-04 | — | — | US | disclosed |
| US-20110082325-A1 | TRANSITION METAL COMPLEX COMPOUNDS, OLEFIN OLIGOMERIZATION CATALYSTS INCLUDING THE COMPOUNDS, AND PROCESSES FOR PRODUCING OLEFIN OLIGOMERS USING THE CATALYSTS | MITSUI CHEMICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| EP-2174928-A1 | TRANSITION METAL COMPLEX COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE COMPOUND, AND METHOD FOR PRODUCING OLEFIN POLYMER PERFORMED IN THE PRESENCE OF THE CATALYST | Mitsui Chemicals, Inc. (JP) | 2010-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082325-A1 | TRANSITION METAL COMPLEX COMPOUNDS, OLEFIN OLIGOMERIZATION CATALYSTS INCLUDING THE COMPOUNDS, AND PROCESSES FOR PRODUCING OLEFIN OLIGOMERS USING THE CATALYSTS | OSTC, COG4, COG7 | ALDH1A1 2282/4885ADRA2B 4317/4885PTGS1 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.