Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Nitrobenzaldehyde SCHEMBL5654 | 0.84 | ERN1 (0.66) | ERN1ALDH1A1MAPTRAB9ANPC1 | |
| 2-Nitrobenzaldehyde SCHEMBL29672618 | 0.84 | ERN1 (0.66) | ERN1ALDH1A1MAPTRAB9ANPC1 | |
| 2-Nitrobenzaldehyde SCHEMBL28981617 | 0.82 | ERN1 (0.63) | ERN1ALDH1A1MAPTTDP1XDH | |
| 2-Nitrobenzaldehyde SCHEMBL28865451 | 0.82 | ERN1 (0.63) | ERN1MAPTRAB9ANPC1TDP1 | |
| 2-Nitrobenzaldehyde SCHEMBL9323445 | 0.82 | ERN1 (0.63) | ERN1ALDH1A1MAPTRAB9ANPC1 | |
| 2-Nitrobenzaldehyde SCHEMBL27794898 | 0.82 | ERN1 (0.63) | ERN1ALDH1A1MAPTRAB9ANPC1 | |
| Pyrrolidine SCHEMBL27371807 | 0.81 | MAPT (0.53) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| 2-Nitrobenzaldehyde SCHEMBL9812419 | 0.81 | ERN1 (0.61) | ERN1ALDH1A1MAPTRAB9ANPC1 | |
| 2-Nitrobenzaldehyde SCHEMBL27303251 | 0.81 | ERN1 (0.61) | ERN1ALDH1A1MAPTRAB9ANPC1 | |
| Ortho-Phthalaldehyde SCHEMBL7621085 | 0.80 | LMNA (0.59) | ERN1ALDH1A1RAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932316-B2 | Two endcapped polymers, one by a hydroxyl or amine group, and the other by a nitrobenzaldehyde piperidine hydrazone group, and a uniformly distributed particulate filler; exhibits both an increased gum viscosity and a decreased compound viscosity; improved rolling resistance, fuel efficiency | BRIDGESTONE CORPORATION (JP) | 2011-04-26 | — | — | US | claimed |
| US-20080161478-A1 | PROCESSABLE RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2008-07-03 | — | — | US | claimed |