Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16832401 | 0.87 | SMN1; SMN2 (0.58) | NPC1RAB9ASMN1; SMN2HTTMEN1 | |
| SCHEMBL16832297 | 0.76 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2CYP2C19LMNA | |
| SCHEMBL18482877 | 0.71 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL11611124 | 0.70 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19LMNA | |
| SCHEMBL16855655 | 0.69 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2CYP2C19LMNA | |
| SCHEMBL19002769 | 0.68 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2CYP2C19LMNA | |
| SCHEMBL11611800 | 0.68 | PTGDR2 (0.45) | NPC1RAB9ASMN1; SMN2CYP2C19LMNA | |
| SCHEMBL16855481 | 0.67 | GAA (0.57) | SMN1; SMN2LMNAGAAHTTMEN1 | |
| SCHEMBL18484094 | 0.67 | ALDH1A1 (0.45) | SMN1; SMN2CYP2C19LMNAGAAHTT | |
| SCHEMBL16855409 | 0.66 | ALDH1A1 (0.44) | NPC1RAB9ALMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091428-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |