Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685564 | 1.00 | MGLL (0.36) | MGLLCES2CES1CTSKHDAC8 | |
| SCHEMBL12087608 | 0.79 | MGLL (0.31) | MGLLCES2CES1 | |
| SCHEMBL4866385 | 0.76 | CES2 (0.40) | MGLLCES2CES1CTSKHDAC8 | |
| SCHEMBL4866380 | 0.76 | CES2 (0.40) | MGLLCES2CES1CTSKHDAC8 | |
| SCHEMBL4866389 | 0.76 | CES2 (0.40) | MGLLCES2CES1CTSKHDAC8 | |
| SCHEMBL21181910 | 0.74 | — | — | |
| SCHEMBL2352505 | 0.74 | CES2 (0.41) | MGLLCES2CES1CTSKHDAC8 | |
| SCHEMBL9876587 | 0.74 | CES2 (0.41) | MGLLCES2CES1CTSKHDAC8 | |
| SCHEMBL1288230 | 0.74 | CES2 (0.41) | MGLLCES2CES1CTSKHDAC8 | |
| SCHEMBL23606015 | 0.71 | MGLL (0.36) | MGLLCES2CES1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307468-B1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN ISOTACTIC COPOLYMER OBTAINED BY HOMOGENOUS CATALYSIS | PIRELLI (IT) | 2012-06-13 | — | — | EP | claimed |
| EP-2307468-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN ISOTACTIC COPOLYMER OBTAINED BY HOMOGENOUS CATALYSIS | Pirelli Tyre S.P.A. (IT) | 2011-04-13 | — | — | EP | claimed |
| WO-2010006655-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN ISOTACTIC COPOLYMER OBTAINED BY HOMOGENOUS CATALYSIS | PIRELLI TYRE S.P.A. (IT) | 2010-01-21 | — | — | WO | claimed |
| EP-2307468-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN ISOTACTIC COPOLYMER OBTAINED BY HOMOGENOUS CATALYSIS | Pirelli Tyre S.P.A. (IT) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010006655-A1 | TYRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION COMPRISING AN ISOTACTIC COPOLYMER OBTAINED BY HOMOGENOUS CATALYSIS | PIRELLI TYRE S.P.A. (IT) | 2010-01-21 | — | — | WO | disclosed |