Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352505 | 1.00 | CES2 (0.41) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL1288230 | 1.00 | CES2 (0.41) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL11789278 | 0.97 | — | — | |
| SCHEMBL4834075 | 0.84 | — | — | |
| SCHEMBL4834078 | 0.84 | — | — | |
| SCHEMBL27342330 | 0.80 | CES2 (0.39) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL3019233 | 0.78 | CES2 (0.38) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL3019236 | 0.78 | CES2 (0.38) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL9656002 | 0.76 | CES2 (0.36) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL23231172 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208891-A1 | HYDROGENATION OF DIENALS OR DIENONES WITH RHODIUM COMPLEXES UNDER CARBON MONOXIDE FREE ATMOSPHERE | FIRMENICH & CIE (CH) | 2024-06-27 | — | — | US | disclosed |
| US-5004815-A | Combining thioc ester with ketone or aldehyde to form adduct, cyclization | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1991-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208891-A1 | HYDROGENATION OF DIENALS OR DIENONES WITH RHODIUM COMPLEXES UNDER CARBON MONOXIDE FREE ATMOSPHERE | ENO1, DECR1, CPNE4 | CES2 2208/4885CES1 2808/4885MGLL 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.