⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20250985 | 0.92 | — | — | |
| SCHEMBL16855748 | 0.92 | MAPT (0.30) | — | |
| SCHEMBL20250982 | 0.85 | — | — | |
| SCHEMBL16855770 | 0.77 | TDP1 (0.43) | — | |
| SCHEMBL17198552 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL18512857 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL25329128 | 0.75 | MAPT (0.30) | — | |
| SCHEMBL25329297 | 0.75 | LMNA (0.32) | — | |
| SCHEMBL18512719 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL16855594 | 0.74 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683321-B2 | 4′-or nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180162898-A1 | 4'-OR NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2018-06-14 | — | — | US | disclosed |
| WO-2015095419-A1 | 4'-OR NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2015-06-25 | — | — | WO | disclosed |