SCHEMBL25329128

SCHEMBL25329128

CC(=O)O[C@@H]1[CH]OC(n2ccc(-n3cncn3)nc2=O)[C@@H]1OC(C)=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25329297 0.82 LMNA (0.32) MAPT
SCHEMBL18503481 0.77 LMNA (0.32) MAPT
SCHEMBL18512719 0.76 LMNA (0.42) MAPT
SCHEMBL16855748 0.76 MAPT (0.30) MAPT
SCHEMBL20250982 0.76
SCHEMBL20250985 0.76
SCHEMBL17198552 0.75 ALDH1A1 (0.39) MAPT
SCHEMBL18512857 0.75 ALDH1A1 (0.39) MAPT
SCHEMBL16855720 0.75
SCHEMBL19882037 0.73 POLA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142803-A1 ANTIVIRAL COMPOUND AND USE THEREOF 北京恩泰伟医药科技有限公司 2023-08-03 WO disclosed