Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259602 | 0.90 | SIGMAR1 (0.71) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL21961925 | 0.90 | SIGMAR1 (0.71) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| Bromide SCHEMBL1259195 | 0.88 | SIGMAR1 (0.69) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL28623314 | 0.84 | CXCR4 (0.70) | CXCR4SIGMAR1CHRM3MEN1KMT2A | |
| SCHEMBL674945 | 0.82 | CXCR4 (0.75) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL674847 | 0.82 | CXCR4 (0.65) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL14895279 | 0.81 | CXCR4 (0.82) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL15855010 | 0.81 | SIGMAR1 (0.59) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL1882484 | 0.80 | CXCR4 (0.78) | CXCR4SIGMAR1CHRM3MEN1CHRM2 | |
| SCHEMBL29823307 | 0.80 | CXCR4 (0.78) | CXCR4SIGMAR1CHRM3MEN1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089639-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-25 | — | — | WO | disclosed |