Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15854996 | 0.98 | SIGMAR1 (0.61) | SIGMAR1NCF1CXCR4MEN1CHRM2 | |
| SCHEMBL1259602 | 0.90 | SIGMAR1 (0.71) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL21961925 | 0.90 | SIGMAR1 (0.71) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| Bromide SCHEMBL1259195 | 0.88 | SIGMAR1 (0.69) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL17169640 | 0.83 | NCF1 (0.51) | SIGMAR1NCF1HRH3KDM4EALDH1A1 | |
| SCHEMBL674847 | 0.82 | CXCR4 (0.65) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL674945 | 0.82 | CXCR4 (0.75) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL15265439 | 0.82 | AGXT (0.56) | SIGMAR1NCF1ADRA2CKDM4EALDH1A1 | |
| SCHEMBL11196105 | 0.81 | NCF1 (0.83) | NCF1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL16855796 | 0.81 | CXCR4 (0.63) | SIGMAR1CXCR4MEN1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062009-B2 | Macrocyclic compounds and metal complexes for bioimaging and biomedical applications | NATIONAL YANG MING UNIVERSITY (TW) | 2015-06-23 | — | — | US | disclosed |
| US-9062009-B2 | Macrocyclic compounds and metal complexes for bioimaging and biomedical applications | NATIONAL YANG MING UNIVERSITY (TW) | 2015-06-23 | — | — | US | disclosed |
| US-20140187527-A1 | Macrocyclic Compounds And Metal Complexes For Bioimaging And Biomedical Applications | NATIONAL YANG MING UNIVERSITY (TW) | 2014-07-03 | — | — | US | disclosed |
| US-20140187527-A1 | Macrocyclic Compounds And Metal Complexes For Bioimaging And Biomedical Applications | NATIONAL YANG MING UNIVERSITY (TW) | 2014-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187527-A1 | Macrocyclic Compounds And Metal Complexes For Bioimaging And Biomedical Applications | DNASE1L3, DNASE1, SNRPA | SIGMAR1 4596/4885NCF1 727/4885CXCR4 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.