Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134235 | 0.91 | PTGS2 (0.48) | PTGS2PTGS1PDGFRBPDGFRA | |
| SCHEMBL16855916 | 0.89 | PTGS2 (0.50) | PTGS2PTGS1TDP2CD274CYP17A1 | |
| SCHEMBL16856038 | 0.89 | PTGS2 (0.47) | PTGS2PTGS1CD274CYP17A1TUBB1 | |
| SCHEMBL16852368 | 0.88 | PTGS2 (0.49) | PTGS2PTGS1TDP2CD274RAB9A | |
| SCHEMBL18134236 | 0.87 | PTGS2 (0.43) | PTGS2PTGS1TDP2CD274RAB9A | |
| SCHEMBL18134240 | 0.87 | PTGS2 (0.43) | PTGS2PTGS1TDP2CD274AR | |
| SCHEMBL16855847 | 0.86 | PTGS2 (0.50) | PTGS2PTGS1TDP2ARERN1 | |
| SCHEMBL17193138 | 0.85 | PTGS2 (0.43) | PTGS2PTGS1CD274RAB9ANPC1 | |
| SCHEMBL16855903 | 0.85 | FPR2 (0.42) | PTGS2PTGS1CD274CYP17A1PRKCZ | |
| SCHEMBL16855900 | 0.85 | PTGS2 (0.44) | PTGS2PTGS1TDP2CD274CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886627-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20170306232-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |